Bridge to Life - Breakfast Symposium
Scaling Better Outcomes:
The Role of HOPE in Contemporary Transplant Programs
Monday, September 21, 2026
Session I: HOPE in Contemporary Clinical Practice
HOPE in Clinical Practice: Workflow, Latest Data, and Outcome Trends
Dr. Anji Wall, The University of Alabama at Birmingham
Topics covered:
- Practical workflow integration and operational simplicity
- Reproducibility across diverse transplant programs
- Latest clinical data
- Comparative positioning: HOPE vs. Normothermic Machine Perfusion (NMP)
- Sequential and combination approaches (e.g., NRP + HOPE)
- Special considerations: prolonged perfusion, split liver grafts
Session II: Viability Assessment in HOPE‑Supported Transplantation
Viability Assessment: Current Approaches and Evolving Standards
Dr. Andrea Schlegel, Cleveland Clinic
Topics covered:
- Key biomarkers and functional parameters
- HOPE‑specific viability insights vs. traditional assessment
- Impact of perfusion duration and graft type
- Considerations for extended criteria donors
Session III: Extended Applications of HOPE
Beyond Standard Use: Pediatric, Living Donor, Surgical, Multivisceral, and Intestinal Applications
Dr. Francisco Hernández Oliveros, Hospital Universitario La Paz (Madrid)
Topics covered:
- Pediatric adaptations and outcome considerations
- Living donor graft optimization
- Surgical applications and intraoperative strategies (i.e. HOPE for cooling during complex hepatectomies)
- HOPE in multivisceral and intestinal transplantation
- Opportunities for innovation and program expansion
Q&A and Discussion
Speakers and moderators
- Andrea Schlegel, Cleveland, OH, USA,
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Dr. Andrea Schlegel
Dr. Andrea Schlegel is an academic transplant surgeon at Cleveland Clinic specialized in liver transplantation and hepatobiliary surgery. Dr. Schlegel’s interests include both, experimental and clinical research with a focus on organ preservation to improve the utilization of human organs. To ensure utmost safety for transplant recipients, Dr. Schlegel’s lab explores underlying mechanisms of mitochondrial injury and protection throughout the entire journey of an organ from the donor to the recipient.
Dr. Schlegel obtained her medical degree with Honors from the Justus-Liebig-University Giessen (Germany). She completed her research fellowship and residency at the University Hospital Zurich (Switzerland), where she also served as Chief Resident and Staff Surgeon with a focus on quality improvement and patient safety in abdominal surgery and transplantation. She went on to complete her Transplant Surgery and Hepato-Pancreatico-Biliary Surgery fellowship training at Queen Elizabeth University Hospital Birmingham (United Kingdom) and was awarded with a Staff position as Transplant Surgeon before moving to Italy (Careggi Hospital Florence and Milan Policlinico), where she achieved the “National Scientifica Qualification” as Full Professor (06/C1 - General Surgery).
Since 2011 her research is focused on a broad range of topics including dynamic organ preservation in context of transplantation, the development of new markers to predict organ viability, and underlying mechanisms of ischemia and reperfusion injury triggered by mitochondrial injury and dysfunction.
Dr. Schlegel serves as Associated Editor and Reviewer in more than 15 leading journals in the field of surgery and transplantation and has various international collaborations worldwide with an average number of 20 invited lectures and presentations per year.
Dr. Schlegel is board certified in General Surgery (FMH), Transplant Surgery (EBSQ/UEMS) and Hepato-Pancreatico-Biliary Surgery (EBSQ/UEMS) and obtained a Master in Business Administration (MBA, specialized in International Healthcare Management) from the Robert Kennedy College (Switzerland) and University of Cumbria (United Kingdom).
Dr. Francisco Hernandez Oliveros
Dr. Francisco Hernandez Oliveros is a renowned pediatric surgeon with more than 20 years of clinical experience. He specialises in digestive, thoracic, plastic and urological surgery, with special dedication to the treatment of congenital malformations. Its comprehensive approach also includes prenatal consultation, key to guiding diagnosis and making clinical decisions from the earliest stages of fetal development.
Dr. Anji Wall
Dr. Anji Wall attended medical school and completed her Doctor of Philosophy in Health Care Ethics at Saint Louis University. She then completed her general surgery residency at Vanderbilt University and subsequently relocated to Stanford University for her fellowship in abdominal transplantation.
A dedicated surgeon scientist, Dr. Wall has published 129 research articles; authored the book, Ethics for International Medicine: A Practical Guide for Aid Workers in Developing Countries; and completed an additional seven book chapters spanning topics from surgical ethics to transplantation. She currently serves on the editorial boards for Liver Transplantation, Frontiers in Transplantation, and the American Journal of Surgery.
In addition to her outstanding contributions to the literature of surgical research, Dr. Wall is an in-demand faculty presenter, who has delivered over 110 grand rounds and visiting professor lectures. A member of numerous surgical societies, including the American Society of Transplant, the American Society of Transplant Surgeons, and the Consortium for Surgical Ethics , she has delivered over 100 conference presentations.
Recognized for her pioneering findings in the field of transplantation, Dr. Wall has been awarded the Visionary Leader Award by the Alliance for Organ Donation and Transplantation and the Rising Star in Transplantation Surgery recognition from the American Society of Transplant Surgeons.